Descripción
The authoritative reference, written with a framework for understanding
the definitive reference text for biochemistry Lehninger Principles of Biochemistry, 8e helps students focus on the most important aspects of biochemistry– the principles! Dave Nelson, Michael Cox, and new co-author Aaron Hoskins identify the most important principles of biochemistry and direct student attention to these with icons and resources targeted to each principle.
The 8th edition has been fully updated for focus, approachability, and up-to-date content. New and updated end-of-chapter questions.
These questions went through a rigorous development process to ensure they were robust, engaging and accurate.
Lehninger Principles of Biochemistry, 8e continues to help students navigate the complex discipline of biochemistry with a clear and coherent presentation. Renowned authors David Nelson, Michael Cox, and new co-author Aaron Hoskins have focused this eighth edition around the fundamental principles to help students understand and navigate the most important aspects of biochemistry. Text features and digital resources in the new Achieve platform emphasize this focus on the principles, while coverage of recent discoveries and the most up-to-date research provide fascinating context for learning the dynamic discipline of biochemistry.
Table of Contents
Preface viii
1. The Foundations of Biochemistry
I STRUCTURE AND CATALYSIS
2. Water, the Solvent of Life
3. Amino Acids, Peptides, and Proteins
4. The Three-Dimensional Structure of Proteins
5. Protein Function
6. Enzymes
7. Carbohydrates and Glycobiology
8. Nucleotides and Nucleic Acids
9. DNA-Based Information Technologies
10. Lipids 11. Biological Membranes and Transport
12. Biochemical Signaling
II BIOENERGETICS AND METABOLISM
13. Introduction to Metabolism
14. Glycolysis, Gluconeogenesis, and the Pentose Phosphate Pathway
15. The Metabolism of Glycogen in Animals
16. The Citric Acid Cycle
17. Fatty Acid Catabolism
18. Amino Acid Oxidation and the Production of Urea
19. Oxidative Phosphorylation
20. Photosynthesis and Carbohydrate Synthesis in Plants
21. Lipid Biosynthesis
22. Biosynthesis of Amino Acids, Nucleotides, and Related Molecules
23. Hormonal Regulation and Integration of Mammalian Metabolism
III INFORMATION PATHWAYS
24. Genes and Chromosomes
25. DNA Metabolism
26. RNA Metabolism 27. Protein Metabolism
28. Regulation of Gene Expression
Abbreviated Solutions to Problems
Glossary
Authors
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David L. Nelson
David L. Nelson, born in Fairmont, Minnesota, received his BS inchemistry and biology from St. Olaf College in 1964, and earned his PhD inbiochemistry at Stanford Medical School, under Arthur Kornberg. He was apostdoctoral fellow at the Harvard Medical School with Eugene P. Kennedy,who was one of Albert Lehninger’s first graduate students. Nelson joinedthe faculty of the University of Wisconsin–Madison in 1971 and became afull professor of biochemistry in 1982. For eight years he was Director ofthe Center for Biology Education at the University of Wisconsin–Madison. Hebecame Professor Emeritus in 2013. Nelson’s research focused on the signaltransductions that regulate ciliary motion and exocytosis in the protozoanParamecium. For 43 years he taught (with Mike Cox) an intensive survey ofbiochemistry for advanced biochemistry undergraduates in the life sciences.He has also taught graduate courses on membrane structure and function, aswell as on molecular neurobiology. He has received awards for hisoutstanding teaching, including the Dreyfus Teacher–Scholar Award and theAtwood Distinguished Professorship. In 1991–1992 he was a visitingprofessor of chemistry and biology at Spelman College. Nelson’s second loveis history, and in his dotage he teaches the history of biochemistry andcollects antique scientific instruments.
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Michael Cox
Michael M. Cox was born in Wilmington, Delaware. In his first biochemistry course, the first edition of Lehninger’s Biochemistry was a major influence in refocusing his fascination with biology and inspiring him to pursue a career in biochemistry. After graduate work at Brandeis University with William P. Jencks and post-doctoral work at Stanford with I. Robert Lehman, he moved to the University of Wisconsin–Madison in 1983. He became a full professor of Biochemistry in 1992.
Mike Cox has coordinated an active research team at Wisconsin investigating the function and mechanism of enzymes that act at the interface of DNA replication, repair, and recombination. That work has resulted in over 200 publications to date.
For more than three decades, Cox has taught introductory biochemistry to undergraduates and has lectured in a variety of graduate courses. He organized a course on professional responsibility for first-year graduate students and established a systematic program to draw talented biochemistry undergraduates into the laboratory at an early stage of their college career. He has received multiple awards for both his teaching and his research, including the Eli Lilly Award in Biological Chemistry, election as an AAAS fellow, and the UW Regents Teaching Excellence Award. Cox’s hobbies include turning 18 acres of Wisconsin farmland into an arboretum, wine collecting, and assisting in the design of laboratory buildings.
Product Details
Publisher: W.H. Freeman, 8th edition
Book Format: eBook, PDF
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